Dr. Austin Perlmutter

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A physician's clear-eyed guide to what the science really says about extending your healthspan — separating proven levers from expensive noise. Written by a brain-health researcher who runs his own longevity trials.

Unhelpful longevity advice has become a billion-dollar business.

Everyone wants to live a long and healthy life, but from peptides to supplements to fancy gadgets and more, most of what you’re being sold is based on precious little science (and a whole lot of marketing dollars). This guide is built to tell you exactly what the real research says, without overpromising or distracting you from the best tools that are shown to work right now.

Healthspan Over Lifespan

Why living longer matters far less than living well — and how to actually measure the difference.

What Actually Drives Aging

Inflammation, mitochondrial decline, and the epigenetic clock — the real biology behind getting old.

The Single Best "Longevity Drug"

It's not a supplement, and it's free. The evidence behind the single highest-leverage habit.

Nutrition Without the Noise

Cut through fad diets to the handful of eating patterns actually linked to slower aging.

Polyphenols & the Cutting Edge

The plant compounds with the strongest emerging data for healthy aging — and how to get enough.

Protecting the Aging Brain

The specific, research-backed levers for cognitive resilience as you get older.

Sleep, Stress, Purpose & Connection

The overlooked pillars of aging well that have nothing to do with pills or protocols.

The Emerging Frontier

A clear-eyed look at peptides, NAD+, and the experimental therapies everyone's asking about.

Testing & Tracking

Which biomarkers are actually worth measuring, and how to interpret them without a lab coat.

Your Slow-Aging Blueprint

A simple, step-by-step plan that pulls every chapter together into daily action.

THE PROOF

In a 90-day clinical trial, we saw a certain set of plant nutrients slow a marker of biological aging by 47% in "fast agers."

Dr. Austin Perlmutter has actively published research on the topic of longevity, but some of the biggest findings are on topics you’ve probably never heard of.

This guide makes that science accessible — and gives you a practical blueprint to act on it today.

"We didn't expect a 90-day lifestyle intervention to meaningfully shift an epigenetic clock — but the data was clear."

• Austin Perlmutter, MD

You're overwhelmed by conflicting longevity advice and don't know who to trust.

You want to protect your brain and memory as you get older.

You want real science, not a sales pitch for the latest supplement.

You'd rather master the basics than chase the newest trend.

Austin Perlmutter, MD

Austin Perlmutter, MD is a physician, brain health researcher, New York Times bestselling author, and educator focused on helping people understand the science of brain health, nutrition, metabolism, and behavior change. He is the co-author of Brain Wash with David Perlmutter, MD.

His work has been featured across major media and read by millions, with a focus on translating complex science into practical steps for a healthier brain and body.